| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| LPXN | Leupaxin | Adaptor Protein | Self-Sufficiency in Growth Signal | Cell Proliferation | Leupaxin(LPXN) knock down significantly reduces proliferation rate of LNCaP cells. | Reference |
| LPXN | Leupaxin | Adaptor Protein | Genome Instability, Mutation & Perturbation | Overexpression | Leupaxin(LPXN) mRNA is overexpressed in human prostate cancer and expression intensities strongly correlates with gleason score. | Reference |
| LPXN | Leupaxin | Adaptor Protein | Metastasis | Cell Invasion | Plays a crucial role in prostate cancer cell invasion through transcriptional coactivation of AR in androgen independent prostate cancer cell line. | Reference |
| LPXN | Leupaxin | Adaptor Protein | Metastasis | Cell Invasion | Leupaxin(LPXN) is involved in prostate cancer invasion in TRAMP mice (transgenic adenocarcinoma of mouse prostate) model via downregulation of cell-cell adhesion protein p120catenin (p120CTN). | Reference |
| LPXN | Leupaxin | Adaptor Protein | Metastasis | Cell Motility | Leupaxin(LPXN) is involved in prostate cancer cell migration through coacivator of Androgen receptor(AR) dependent way in LNCaP cell line. | Reference |
| LPXN | Leupaxin | Adaptor Protein | Metastasis | Cell Adhesion | Mediates prostate cancer cell adhesion in androgen dependent and independent cell line. | Reference |
| LPXN | Leupaxin | Adaptor Protein | Metastasis | Cell Migration | (LPXN) regulates prostate cancer cell migration through the complex formation with Pyk2, c-Src, and PTP-PEST in androgen independent prostate cancer cell line PC-3. | Reference |