| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| RUNX2 | Runt-related transcription factor 2 | Transcription Factor | Self-Sufficiency in Growth Signal | Cell Growth | RUNX2 is involved in prostate cancer cell growth in an androgen responsive ways. | Reference |
| RUNX2 | Runt-related transcription factor 2 | Transcription Factor | Metastasis | Cell Invasion | RUNX2 play an important role in prostate cancer cell invasion through regulating matrix metaloproteinase 9 in bone metastatic prostate cancer cell. | Reference |
| RUNX2 | Runt-related transcription factor 2 | Transcription Factor | Metastasis | Cell Migration | RUNX2 is involved in prostate cancer cell migration as FOXO1 targets and inhibits RUNX2 and causes suppression of prostate cancer cell migration . | Reference |
| RUNX2 | Runt-related transcription factor 2 | Transcription Factor | Metastasis | Bone Metastasis | RUNX2 is involved in the bone metastasis of prostate cancer through alphavbeta3 integrin-Smad5-RUNX2-receptor activator of NF-kB ligand (RANKL) signaling axis. | Reference |
| RUNX2 | Runt-related transcription factor 2 | Transcription Factor | Cell Death Resistance | Aoptosis Resistance | RUNX2 is involved in apoptosis resistance of prostate cancer by modulating expressiopn of BCL2. | Reference |
| RUNX2 | Runt-related transcription factor 2 | Transcription Factor | Metastasis | Cell Invasion | It's a osteogenic transcription factor and regulates cell invasion in androgen independent prostate cancer cell line. | Reference |
| RUNX2 | Runt-related transcription factor 2 | Transcription Factor | Self-Sufficiency in Growth Signal | Cell Growth | Nitric oxide regulates RUNX2 (a transcription factor), which is highly expressed in human prostate tumour and plays a role in prostate cancer cell growth. | Reference |