| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| SOCS3 | Suppressor of cytokine signaling 3 | Adaptor Protein | Self-Sufficiency in Growth Signal | Cell Survival | SOCS3 plays an important role in castration resistant prostate cancer cell survival. | Reference |
| SOCS3 | Suppressor of cytokine signaling 3 | Adaptor Protein | Genome Instability, Mutation & Perturbation | Overexpression | SOCS3 is overexpressed in castration resistant prostate tumour | Reference |
| SOCS3 | Suppressor of cytokine signaling 3 | Adaptor Protein | Metastasis | Cell Proliferation | Inhibition of SOCS3 by siRNA results in suppression of proliferation in prostate cancer cells | Reference |
| SOCS3 | Suppressor of cytokine signaling 3 | Adaptor Protein | Cell Death Resistance | Aoptosis Resistance | SOCS3 antagonize and influence TRAIL and resveratrol mediated apoptosis in prostate cancer cell line DU145 cells. | Reference |
| SOCS3 | Suppressor of cytokine signaling 3 | Adaptor Protein | Cell Death Resistance | Apoptosis Evasion | It mediates regulation of apoptosis & its function has been implicated in the cell survival machinery of both androgen dependent & independent prostate cancer cell line; it is overexpressed in castration resistant tumour. | Reference |