Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
KRASKirsten rat sarcoma viral oncogene homologGTPaseSelf-Sufficiency in Growth SignalCell ProliferationKRAS is involved in prostate cancer cell proliferation as miR-143 targets KRAS suppressed prostate cancer cell proliferation.Reference
KRASKirsten rat sarcoma viral oncogene homologGTPaseGenome Instability, Mutation & PerturbationMutationMutation in KRAS gene causes oncogenic activation and plays a role in prostate cancer development and pathogenesis in Japanese men.Reference
KRASKirsten rat sarcoma viral oncogene homologGTPaseGenome Instability, Mutation & PerturbationMutationMutation in KRAS gene has been found in prostate adenocarcinoma.Reference
KRASKirsten rat sarcoma viral oncogene homologGTPaseMetastasisCell MigrationPromotes cell migration through EGFR/RAS/MAPK pathway in prostate cancer tissues and androgen independent prostate cancer cell lines.Reference

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