Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
PDE4DPhosphodiesterase 4D, cAMP-specificEnzyme PhosphodiesteraseSelf-Sufficiency in Growth SignalCell GrowthPDE4D is involved in prostate cancer cell growth as knock down of this gene reduced the growth rate of prostate cancer cells in vivo.Reference
PDE4DPhosphodiesterase 4D, cAMP-specificEnzyme PhosphodiesteraseSelf-Sufficiency in Growth SignalCell ProliferationPDE4D is associated with prostate cancer as a proliferation promoting factor as knockdown of this gene suppressed the the proliferation rate of prostate cancer xenograft in vivo.Reference
PDE4DPhosphodiesterase 4D, cAMP-specificEnzyme PhosphodiesteraseMetastasisCell MigrationPDE4D is involved in prostate cancer cell migration as knock down of this gene reduced the cell migration rate of prostate cancer cell in vivo.Reference

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