Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
BCL2L1BCL2-like 1Adaptor ProteinSelf-Sufficiency in Growth SignalCell SurvivalBCL2L1 is involved in prostate cancer cell survival through interaction with proapoptotic BAKReference
BCL2L1BCL2-like 1Adaptor ProteinSelf-Sufficiency in Growth SignalCell SurvivalBCL2L1 is involved in prostate tumour cell survival by AR induced Integrin alpha6beta1 mediated mannerReference
BCL2L1BCL2-like 1Adaptor ProteinGenome Instability, Mutation & PerturbationOverexpressionBCL2L1 is overexpressed and contributes to androgen resistance in prostate cancerReference
BCL2L1BCL2-like 1Adaptor ProteinInsensitivity to Anti-Growth SignalCell CycleBCL2L1(BCL-XL), which is overexpressed in human prostate cancer plays a role in G1 to S phase transition of prostate cancer cell cycle in an androgen receptor(AR) dependent manner.Reference

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