| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| FADD | Fas (TNFRSF6)-associated via death domain | Adaptor Protein | Self-Sufficiency in Growth Signal | Cell Survival | Strongly influences prostate cancer cell survival by modulating hTERT expression and telomerase activity in androgen independent prostate cancer cell line. | Reference |
| FADD | Fas (TNFRSF6)-associated via death domain | Adaptor Protein | Metastasis | Cell Invasion | Influences prostate cancer cell invasion through modulation of human telomerase reverse transcriptase expression. | Reference |
| FADD | Fas (TNFRSF6)-associated via death domain | Adaptor Protein | Cell Death Resistance | Aoptosis Resistance | It is involved in in PTEN mediated apoptosis for both death receptor mediated & drug induced apoptosis in androgen dependent prostate cancer cell line: plays a role in apoptosis resistance & chemoresistance due to PTEN loss of function. | Reference |
| FADD | Fas (TNFRSF6)-associated via death domain | Adaptor Protein | Enabling Replicative Immortality | Telomere maintenance | Phosphorylation of FADD is associated with modulation of Telomerase & Telomerase reverse transcriptase activity in prostate cancer | Reference |
| FADD | Fas (TNFRSF6)-associated via death domain | Adaptor Protein | Insensitivity to Anti-Growth Signal | Cell Cycle | Adapter protein FADD is critically involved in prostate cancer associated G2 to M phase cell cycle transition. | Reference |