| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| FGFR1 | Fibroblast growth factor receptor 1 | Receptor Tyrosine Kinase | Self-Sufficiency in Growth Signal | Cell Growth | Androgen insensitive prostate cancer in vivo cell growth is mediated by FGF7 and its receptor FGFR1 under condition of androgen ablation. | Reference |
| FGFR1 | Fibroblast growth factor receptor 1 | Receptor Tyrosine Kinase | Self-Sufficiency in Growth Signal | Cell Proliferation | FGF2 & its receptor FGFR1 is involved in prostate cancer epithelial cell proliferation. | Reference |
| FGFR1 | Fibroblast growth factor receptor 1 | Receptor Tyrosine Kinase | Genome Instability, Mutation & Perturbation | Genome Instability | FGF-2/FGFR1/CEP57 signaling axis is involved in mitotic instability of prostate cancer. | Reference |
| FGFR1 | Fibroblast growth factor receptor 1 | Receptor Tyrosine Kinase | Genome Instability, Mutation & Perturbation | Overexpression | FGFR1 is overexpressed in advanced prostate cancer. | Reference |
| FGFR1 | Fibroblast growth factor receptor 1 | Receptor Tyrosine Kinase | Angiogenesis | Angiogenesis | FGFR1 is involved in prostate cancer angiogenesis and angiopoietins functions as downstream effectors of FGFR1 activation, supported by a transgenic mouse model. | Reference |
| FGFR1 | Fibroblast growth factor receptor 1 | Receptor Tyrosine Kinase | Metastasis | Metastasis | FGFR1 is involved in prostate cancer metastasis, supported by transgenic mouse model of prostate cancer. | Reference |
| FGFR1 | Fibroblast growth factor receptor 1 | Receptor Tyrosine Kinase | Metastasis | Epithelial Mesenchymal Transition(EMT) | FGFR1 activation results in epithelial mesenchymal transition in the epithelial compartment during prostate cancer progression. | Reference |
| FGFR1 | Fibroblast growth factor receptor 1 | Receptor Tyrosine Kinase | Metastasis | Cell Migration | FGF2 & its receptor FGFR1 is involved in prostate cancer cell migration. | Reference |
| FGFR1 | Fibroblast growth factor receptor 1 | Receptor Tyrosine Kinase | Insensitivity to Anti-Growth Signal | Cell Cycle | FGFR-1 plays a role in prostate cancer cell cycle progression, through mediating G2 to M phase transition. | Reference |