| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| IL6ST | Interleukin 6 signal transducer | Cytokine Receptor | Self-Sufficiency in Growth Signal | Cell Growth | IL6 enhance prostate cancer cell growth through IL6ST(GP130)-JAK2-STAT3 mediated signaling pathway in LNCaP human prostate cancer cells. | Reference |
| IL6ST | Interleukin 6 signal transducer | Cytokine Receptor | Self-Sufficiency in Growth Signal | Cell Growth | IL6 is an autocrine growth factor mediates its effects on prostate cancer cell growth through JAK-STAT signalin | Reference |
| IL6ST | Interleukin 6 signal transducer | Cytokine Receptor | Self-Sufficiency in Growth Signal | Cell Growth | Prostaglandin E2 enhances prostate cancer cell growth via activation of IL6/IL6ST/STAT3 signaling | Reference |
| IL6ST | Interleukin 6 signal transducer | Cytokine Receptor | Tumor Promoting Inflammation | Inflammation pathway | IL6ST is an inflammation pathway gene and is linked to prostate cancer inflammation. | Reference |
| IL6ST | Interleukin 6 signal transducer | Cytokine Receptor | Tumor Promoting Inflammation | Inflammation | It is involved in prostate cancer inflammation and its genetic polymorphism has been detected in Caucasian population. | Reference |
| IL6ST | Interleukin 6 signal transducer | Cytokine Receptor | Genome Instability, Mutation & Perturbation | Genetic polymorphism | IS6ST gene polmorphism is significantly associated with prostate cancer risks in caucasian | Reference |
| IL6ST | Interleukin 6 signal transducer | Cytokine Receptor | Genome Instability, Mutation & Perturbation | Genetic polymorphism | Single nuceotide polymorphism of the IL6ST gene is significantly associated with prostate cancer risks in Caucasian and african american population. | Reference |