Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
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NGFR | Nerve growth factor receptor | Cell Surface Receptor | Insensitivity to Anti-Growth Signal | Tumor Suppression | NGFR(p75NTR) tumour suppressor is lost during prostate cancer progression and is involved in regulation of apoptosis via intrinsic mitochondrial pathway. | Reference |
NGFR | Nerve growth factor receptor | Cell Surface Receptor | Self-Sufficiency in Growth Signal | Cell Survival | NGFR(p75NTR) and its ligand NGFR is involved in pro survival signaling in prostate cancer. | Reference |
NGFR | Nerve growth factor receptor | Cell Surface Receptor | Genome Instability, Mutation & Perturbation | Loss of Expression | 3' UTR are involved in loss of p75(NTR) expression in prostate cancer. | Reference |
NGFR | Nerve growth factor receptor | Cell Surface Receptor | Metastasis | Metastasis | NGFR(p75NTR) functions as a metastatic suppressor in prostate cancer by down regulation of uPA, MMP-2, MMP-9, and TIMP-1. | Reference |
NGFR | Nerve growth factor receptor | Cell Surface Receptor | Metastasis | Cell Invasion | NGFR(p75NTR) re-expression in stromal smooth muscle cells is related to the prostate cancer tumour cell invasion. | Reference |
NGFR | Nerve growth factor receptor | Cell Surface Receptor | Metastasis | Cell Migration | NGFR(p75NTR) is involved in prostate cancer cell migration via NGFR(p75NTR)-P38mapk-nag1 pathway. | Reference |
NGFR | Nerve growth factor receptor | Cell Surface Receptor | Cell Death Resistance | Apoptosis Evasion | It is involved in intrinsic apoptosis cascade & its loss of expression is associated with apoptosis evasion in androgen independent prostate cancer cell line. | Reference |
NGFR | Nerve growth factor receptor | Cell Surface Receptor | Insensitivity to Anti-Growth Signal | Tumor Suppression | NGFR [p75(NTR)], a tumour suppressor which is lost during the course of prostate tumorigenesis, plays a significant role in regulation of prostate cancer cell cycle. | Reference |