Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
ST7Suppression of tumorigenicity 7Cell Cycle Control ProteinInsensitivity to Anti-Growth SignalTumor SuppressionST7 located on chromosome 7q31.1 functions as a tumour suppressor in prostate cancer by mediating modification of tumour microenvironments.Reference
ST7Suppression of tumorigenicity 7Cell Cycle Control ProteinSelf-Sufficiency in Growth SignalCell GrowthST7 is involved in influencing the prostate cancer cell growth as ST7 suppressed the prostate cancer cell growth of PC-3 prostate cancer cells inoculated subcutaneously into severe combined immunodeficient(SCID) mice.Reference
ST7Suppression of tumorigenicity 7Cell Cycle Control ProteinGenome Instability, Mutation & PerturbationEpigenetic Silencingits primary mechanism of inactivation is via epigenetic downregulation, haplo-insufficiency or post-translational modification of the ST7 proteinReference

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