Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
MAPK14Mitogen-activated protein kinase 14Serine/Threonine KinaseSelf-Sufficiency in Growth SignalCell GrowthMAPK14(p38 alpha) is associated with aggressive growth of prostate cancer cell in LNCaP prostate cancer cell line .Reference
MAPK14Mitogen-activated protein kinase 14Serine/Threonine KinaseMetastasisCell InvasionMAPK14(p38 alpha) along with ERK2 play an important role in the regulation of prostate cancer cancer cell invasion in response of LPA stimulation.Reference
MAPK14Mitogen-activated protein kinase 14Serine/Threonine KinaseMetastasisCell MigrationMAPK14(p38 alpha) is involved in prostate cancer cell migration along with ERK2 in a LPA induced manner in the PC-3 prostate cancer cell line.Reference
MAPK14Mitogen-activated protein kinase 14Serine/Threonine KinaseCell Death ResistanceAoptosis ResistanceMAPK14(p38 alpha) imparts resistance to TNF alpha induced apoptosis in LNCaP prostate cancer cell line.Reference

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