Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
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SRC | V-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | Tyrosine Kinase | Self-Sufficiency in Growth Signal | Cell Growth | SRC play an important role in prostate cancer cell growth through Src/FAK/Rho GTPase signaling pathway. | Reference |
SRC | V-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | Tyrosine Kinase | Angiogenesis | Angiogenesis | SRC is involved in prostate cancer angiogenesis through Src/FAK/Rho GTPase mediated signaling in both androgen dependent & independent prostate cancer cell line.. | Reference |
SRC | V-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | Tyrosine Kinase | Metastasis | Metastasis | SRC kinase is involved in prostate cancer metastasis by regulating the expression of E-cadherin demonstrated by tumour xenograft model. | Reference |
SRC | V-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | Tyrosine Kinase | Metastasis | Cell Motility | SRC is involved in the prostate cancer cell motility along with FAK. | Reference |
SRC | V-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | Tyrosine Kinase | Metastasis | Cell Adhesion | Mediates prostate cancer cell adhesion through beta(1) integrin-RACK1-FAK-SRC signaling pathway in androgen dependent and independent prostate cancer cell line. | Reference |
SRC | V-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | Tyrosine Kinase | Metastasis | Cell Migration | Src is involved in prostate cancer cell migration in a bradykinin dependent ways. | Reference |
SRC | V-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | Tyrosine Kinase | Metastasis | Cell Migration | SRC is involved in prostate cancer cell migration in CCL2 and CCCR2 responsive ways mediated by PKCdelta, c-Src, and AP-1. | Reference |
SRC | V-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | Tyrosine Kinase | Metastasis | Bone Metastasis | SRC kinase play an important role in bone metastasis of prostate cancer. | Reference |
SRC | V-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | Tyrosine Kinase | Metastasis | Lymph node Metastasis | SRC is involved in lymph node metastasis during prostate cancer progression. | Reference |
SRC | V-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | Tyrosine Kinase | Cell Death Resistance | Aoptosis Resistance | SRC is involved in apoptosis resistance in prostate cancer cell through P2Y2/Src/p38/COX-2 pathway. | Reference |
SRC | V-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog | Tyrosine Kinase | Metastasis | Bone Metastasis | It is involved in prostate cancer bone metastasis by playing a role in osteoclast mediated bone resorption, tumour growth and metastasis. | Reference |