Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
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PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | Lipid Kinase | Metabolic Reprogramming | Metabolic Reprogramming | PIK3CB is involved in the metabolic regulation and glucose homeostasis in mouse prostate tumour model through a kinase independent mechanism. | Reference |
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | Lipid Kinase | Self-Sufficiency in Growth Signal | Cell Survival | Involved in cell survival through AKT activation in both androgen dependent & independent prostate cancer cell line. | Reference |
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | Lipid Kinase | Self-Sufficiency in Growth Signal | Cell Growth | PIK3CB is involved in prostate cancer cell growth through PIK3 pathway activation in PTEN deficient prostate tumour xenograft model. | Reference |
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | Lipid Kinase | Self-Sufficiency in Growth Signal | Cell Proliferation | PIK3CB is involved in prostate cancer abnormal cell proliferation through PIK3 pathway activation in PTEN deficient prostate tumour xenograft model. | Reference |