| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| ESR2 | Estrogen receptor 2 (ER beta) | Transcription Factor | Metastasis | Bone Metastasis | Estrogen receptor beta 2 is involved in advanced prostate cancer and play very important role in prostate cancer bone metastasis | Reference |
| ESR2 | Estrogen receptor 2 (ER beta) | Transcription Factor | Enabling Replicative Immortality | Telomere maintenance | Estrogen receptor beta promotes human prostate cancer associated hTERT expression by forming combinatorial complexes ESR2/HIF1A and ESR2/eNOS. | Reference |
| ESR2 | Estrogen receptor 2 (ER beta) | Transcription Factor | Enabling Replicative Immortality | Telomere maintenance | Estrogen receptor beta plays a very important role in modulation of telomerase activity in human prostate cancer. | Reference |