Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
---|---|---|---|---|---|---|
MED1 | Mediator complex subunit 1 | Transcription Regulatory Protein | Insensitivity to Anti-Growth Signal | Tumor Suppression | TGFBR3 functions as a tumour suppressor gene in human prostate cancer; Its loss of expression is mediated by LOH and epigenetic silencing. | Reference |
MED1 | Mediator complex subunit 1 | Transcription Regulatory Protein | Tumor Promoting Inflammation | Inflammation | It is a coactivator of AR and is overexpressed in prostate cancer cell line and clinical prostate tumours. It promoptes number of important genes involved in prostate cancer inflammation. | Reference |