Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
MED1Mediator complex subunit 1Transcription Regulatory ProteinInsensitivity to Anti-Growth SignalTumor SuppressionTGFBR3 functions as a tumour suppressor gene in human prostate cancer; Its loss of expression is mediated by LOH and epigenetic silencing.Reference
MED1Mediator complex subunit 1Transcription Regulatory ProteinTumor Promoting InflammationInflammationIt is a coactivator of AR and is overexpressed in prostate cancer cell line and clinical prostate tumours. It promoptes number of important genes involved in prostate cancer inflammation.Reference

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