| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|---|---|---|---|---|---|
| INS | Insulin | Growth Factor | Tumour Microenvironment | Cancer Microenvironment | Insulin and leptin secreted by pre-adipocyte (one of the basic components in the prostate tumor microenvironment) critically mediated prostate cancer cell proliferation and survival, there by promoting its aggressiveness. | Reference |
| INS | Insulin | Growth Factor | Metastasis | Cell Adhesion | Insulin (INS)/IGF1 plays a role in in mediating adhesion of prostate cancer cells to the vascular endothelial cells through CD44-VCAM-1 interaction. | Reference |