| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|---|---|---|---|---|---|
| TGFB1 | Transforming growth factor, beta 1 | Ligand | Tumour Microenvironment | Cancer Microenvironment | Prostate cancer cells secreted exsomal TGF beta1 is required for differentiation of stromal fibroblast into myofibroblasts and there by promotes the formation of prostate tumour-promoting stroma. | Reference |
| TGFB1 | Transforming growth factor, beta 1 | Ligand | Avoidance of Immune Destruction | Immuno Suppression | TGFbeta1 secreted from CD4+ T cell in human prostate tumour microenvironment inhibit differentiation of CD8+ T cells to cytotoxic T cell and there by contributes to prostate cancer immuno suppression. | Reference |