Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
HIF1AHypoxia inducible factor 1, alpha subunit Transcription FactorEnabling Replicative ImmortalityTelomere maintenanceHIF1A plays a role in human prostate cancer associated hTERT expression by interacting with estrogen receptors.Reference
HIF1AHypoxia inducible factor 1, alpha subunit Transcription FactorTumor Promoting InflammationInflammationHIF1A plays a significant role in human prostate cancer related inflammation through NF-kB activation.Reference
HIF1AHypoxia inducible factor 1, alpha subunit Transcription FactorAngiogenesisAngiogenesisActivation of hypoxia-inducible factor 1A(HIF1A) through interplay between miR-182 and HIF1A results in activation of HIF1A signaling pathway and there by drives human prostate cancer angiogenesis.Reference

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