Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
ID4Inhibitor of DNA binding 4, dominant negative helix-loop-helix proteinTranscription Regulatory ProteinEnabling Replicative ImmortalitySenescence DownmodulationInhibitor of DNA binding 4(ID4), a potential tumor suppressor that is down-regulated through promoter hypermethylation during prostate tumorigenesis, plays a very critical role in induction of senescence program through regulating E2F expresseion.Reference
ID4Inhibitor of DNA binding 4, dominant negative helix-loop-helix proteinTranscription Regulatory ProteinInsensitivity to Anti-Growth SignalTumor SuppressionID4, a member of the Id gene family, functions as an important tumour suppressor in human prostate cancer through influencing cell proliferation.Reference

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