ID4 | Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | Transcription Regulatory Protein | Enabling Replicative Immortality | Senescence Downmodulation | Inhibitor of DNA binding 4(ID4), a potential tumor suppressor that is down-regulated through promoter hypermethylation during prostate tumorigenesis, plays a very critical role in induction of senescence program through regulating E2F expresseion. | Reference |
ID4 | Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | Transcription Regulatory Protein | Insensitivity to Anti-Growth Signal | Tumor Suppression | ID4, a member of the Id gene family, functions as an important tumour suppressor in human prostate cancer through influencing cell proliferation. | Reference |