Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
HLA1Major histocompatibility complex, class I, AMHC Complex ProteinAvoidance of Immune DestructionImmune EvasionHuman leukocyte antigen class I antigens (HLA-I) is downregulated in human prostate cancer in response of EGF and TGF beta mediated signaling, which prevents presentation of antigenic peptides to cytotoxic T lymphocytes and there by facilitates immune evasion.Reference

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