Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
YAP1Yes associated protein 1Transcription Regulatory ProteinCastration ResistanceCastration ResistanceYes-associated protein (YAP), a crucial effector of the hippo tumor suppressor pathway, drives castration resistant prostate cancer (CRPC) development through regulation of cell growth.Reference
YAP1Yes associated protein 1Transcription Regulatory ProteinMetastasisCell MotilityYes-associated protein (YAP), a crucial effector of the hippo tumor suppressor pathway, plays a role in the regulation of human prostate cancer associated cell motility.Reference
YAP1Yes associated protein 1Transcription Regulatory ProteinMetastasisCell InvasionYes-associated protein (YAP), a crucial effector of the hippo tumor suppressor pathway, plays a role in the regulation of human prostate cancer associated cell invasion and there by promotes metastasis..Reference
YAP1Yes associated protein 1Transcription Regulatory ProteinSelf-Sufficiency in Growth SignalCell GrowthYes-associated protein (YAP), a crucial effector of the hippo tumor suppressor pathway, plays a role in the regulation of human prostate cancer associated cell growth and there by mediates castration resistance.Reference

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