| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|---|---|---|---|---|---|
| HSD3B1 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | Enzyme Isomerase | Genome Instability, Mutation & Perturbation | Genetic polymorphism | Allelic variation in HSD3B1 (1245C) is significantly associated with castration resistant prostate cancer (CRPC) progression. | Reference |