| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|---|---|---|---|---|---|
| MMP2 | Matrix metallopeptidase 2 | Metallo Protease | Metastasis | Bone Metastasis | Intramedullary pressure generated by metastatic prostate tumour in bone microenvironment induces osteocytes to release matrix mettaloprotease 2 (MMP2) which in turn mediates intraosseous prostate tumour growth. | Reference |