The new module osprai_one provides access to the important functions in all of the other modules.  Documentation has been started with osprai_one.html.

The new module osprai_one provides access to the important functions in all of the other modules.  Documentation has been started with osprai_one.html.

Added clma(), a constrained LMA fitting function.  We can now set a lower and upper bound for fitting.  Be sure that the initial estimate is between, not at, the bounds.  It transforms the parameters using x1 = ((b-a)*tanh(x0)+b+a)/2 for the interval (a,b).  

Introduction of the fit_module.  This provides ordinary Levenberg-Marquart curvefitting.  The user can choose which model parameters are fixed and which are allowed to float.  Next, we can add a constrained version.

Add a simple 1to1 model function.

Start work on curve fitting.  Added two properties, model and params, to ba.roi in ba_class.  Add mdl_module which will hold functions that model SPR interactions.  

Fix bug in "Next" button script.

Bug fix.

Added features to select time points for measuring binding responses and to output that data to a file or scatterplot.  Added the background subtraction feature to cal_module.  Also a few bug fixes. --CGL

Fixed bugs in cal_module and ba_class where arrays of zeros--empty ROIs--would cause errors.

Addition of cal_module to provide a calibration tool and related features.  Added the time2val function to the ba class.  It has a bug now, but it will be useful for the calibration tool.

Introduce vu_module.py for viewing ba objects.  This GUI uses Tk and has buttons to allow users to move through the sensorgrams six-at-a-time.  The traces can be dotted or continuous lines or both.  Specify two ba objects and the first will be dotted while the second will be continuous.  This could be useful for comparing real and simulated data. --CGL 

Add example-biosensor.txt as a convenience for testing.

Add readbiosensor() and writebiosensor() capabilities to io_module.  

Add four example SPR data files to help in testing code.  --CGL

Initial addition of ba_class, an alternative to SPRdataclass.  This class, ba or Biosensor Array, has one internal structure rather than different internal structures depending on whether SPRit or Biacore or other data was imported.  This makes the code smaller and more readable.  It provides default values, usually 0 or null text, that make it easier to import and export different file formats.  We also add io_module to provide import and export features.  We also add test.py as a convenience for testing and demonstration.

Added CONSTANTS to represent data file type identification integers.  These should be used throughout the code in the future to make it more readable.  Also added some default injection data to make it possible to convert a SPRit file to a CLAMP file without having an Analyte/injection file.  Also note a changed dictionary key IDcal->ID in one instance. --CGL

Changes made to allow use with Linux.  Can now read SPRit and output Clamp formats.  Replace == and != with "in" and "not in" string comparisons.  Change IDcal to ID in line 834.  Add function "method_read_fake" to provide default information.  Change WindowsError exception to OSError exception.  Allow user to specify default pathway for saving files by entering null string "".

Example input data files for testing purposes.

Functions in converter are renamed to conform to python PEP8 style.  Some uppercase names have been made lowercase.

Initial check-in of the html manual for converter.py.

Initial import of Osprai project