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  • Delila-Genome: Protein binding analysis - Downloads

    delila-genome 1.0 (tar/gz)

    Release notes:

    Delila-genome 1.0 is a software system for identification, visualization 
    and analysis of protein binding sites in complete genome sequences.
    Binding sites are predicted by scanning genomic sequences with
    information theory-based (or user-defined) weight matrices.
    Parameters for genome scans are entered using a Java-based GUI 
    interface and backend scripts in Perl. Multi-processor CPU load-sharing
    minimizes average response times for scans of different chromosomes. 
    Individual binding sites are displayed either as high-resolution
    sequence walkers or in low-resolution custom tracks in the UCSC genome
    browser. An HTML document is produced listing binding sites ranked by
    binding site strength or chromosomal location hyperlinked to the UCSC
    custom track, other annotation databases and binding site sequences.  
    Post-genome scan tools parse binding site annotations of selected 
    chromosome intervals and compare the results of genome scans using
    different weight matrices. Comparisons of multiple genome scans can
    display binding sites that are unique to each scan and identify sites
    with significantly altered binding strengths.
    Note: The system requires the Delila package of individual information
    programs which are available from the National Cancer Institute (www.lecb.ncifcrf.gov/~toms/contacts.html).


    Changelog:

     

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