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    Opportunity: Lab Manager in an international high-throughput network biology lab @ Technical University of Denmark -- Lyngby, Denmark
    Submitted by Signatur AS; posted on Thursday, December 06, 2012


    Applications are invited for a Senior Research Technician / Laboratory Manager, to work in the Cellular Signal Integration Group. C-SIG,, is a network biology research group located at the Department of Systems Biology at the Technical University of Denmark (DTU). Our department represents one of the largest network biology centers in academia and has a highly multi-disciplinary profile. In our lab, we explore biological systems by both generating high-throughput data and developing and deploying algorithms aimed at predicting cell behavior with accuracy similar to that of weather or aircraft models. Our focus is on studying cellular signal processing and decision-making.

    Job description:
    A Senior Research/Laboratory Technician / Laboratory Manager position is available in Prof Rune Linding's Cellular Signal Integration Group (C-SIG, at CBS. Prof Linding is a world-leading network and systems biologist whose laboratory is interested in the mechanisms by which cells use signaling networks to respond to changes in their environment. We are seeking highly motivated, bright co-workers and our lab is a dynamic, highly productive and stimulating environment, where we provide world-class multi-disciplinary training.

    In this position, a successful applicant will work in a fast-paced dynamic environment to help manage and support studies to advance research into biological systems in order to develop new understanding and therapies of complex human diseases like cancer. Duties will range from giving input to experimental design, guiding experimental efforts, managing day-to-day lab activities and requirements, to conducting and/or providing experimental work for on-going projects. Duties will also involve managerial and administrative support to Prof Linding.


    We are seeking an experienced and motivated person to manage and work on projects related to our recent studies on phosphorylation networks and network medicine (Creixell et al. 20012 Nature Biotechnology, Erler & Linding Cell 2012, Bakal, Linding et al. Science 2008, Tan et al. Science 2009 and Tan et al. Science 2011 and Jørgensen et al. Science 2009. The projects involve different combinations of RNAi screening, mass-spectrometry, NGS/genomics and large-scale cell culturing to systematically investigate dysregulation of signaling networks in cancer. By combining computational modeling with genomics, quantitative phospho-proteomics and high-throughput imaging we aim to perform global modeling of biological systems and cancer progression.


    Candidates must hold a laboratory technician degree and previous experience from working in an environment with molecular biology, biochemistry, cell biology or a relevant field and have extensive experience of mammalian tissue culture, protein chemistry, proteomics sample prep workflows and general biochemistry skills. Experience of biological mass spectrometry (nLC-ESI-MS), quantitative proteomics or phospho-proteomics and RNAi is a distinct advantage. Experience in project management, budgeting, grant administration and negotiations is desirable.


    The period of employment is permanent.


    DTU offers:
    The C-SIG lab is part of the Center for Biological Sequence Analysis (CBS) at the Technical University of Denmark (DTU). CBS represents one of the largest systems- and computational biology centers in academia and has a highly multi-disciplinary profile. DTU strives for academic excellence, collegial respect and freedom tempered by responsibility. DTU is a leading technical university in Europe and ranks with the best universities in the world. We offer a highly attractive salary and the opportunity to take part in a frontier research program combating cancer.

    Salary and terms of employment:
    Salary and employment conditions are in accordance with the OAO-S joint agreement and association agreement for office workers, laboratory technicians and IT staff (HK/Stat) signed with the Danish Ministry of Finance. The candidate will receive a high monthly retirement supplement in addition to the salary.


    We must have your online application by 20 January 2013. Please apply at - open the link "apply online" below and fill in the application form and attach your publication list, CV and cover letter. Applications should be submitted in English.

    Please do not include reprints of already published papers in your application. The material that should be given consideration in the assessment must be attached.

    Applications and enclosures received after the deadline will not be considered.

    All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

    Further information may be obtained from Professor Rune Linding, +45 2365 1941 or linding[at]

    You can read more about CBS, the Center for Biological Sequence Analysis, on and about Professor Rune Linding's Research Group at


    20 January 2013

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