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    Opportunity: Postdoctoral Research Scientist in Computational Toxicology @ Johns Hopkins CAAT -- RTP, NC and Baltimore, MD (US)
    Submitted by Andre Kleensang; posted on Tuesday, February 12, 2013


    The Johns Hopkins Center for Alternatives to Animal Testing is involved in several scientific projects implementing the vision of Toxicity Testing in the 21st Century as formulated by the National Research Council report in 2007. The center is leading the NIEHS -funded Human Toxome Project, which is collaborative effort between CAAT, Georgetown University, Hamner Institute, Agilent and the US Environmental Protection Agency (EPA) to map pathways of toxicity.


    We are seeking a post-doctoral researcher to analyze and integrate multiple different data streams including, high-throughput screening data from the EPA ToxCast project.

    The candidate will develop/use computational tools to identify and evaluate putative predictors of toxic effects due to endocrine disruption.


    Required skills include empirical analysis of using HTS, metabolomics and proteomics data using machine learning methods, and pathway analysis using in-house and publicly available tools.

    Demonstrated experience with computer programming using open-source tools (R and/or Python) is a must.

    Ph.D. in computational biology/toxicology, bioinformatics, physics, computer science, mathematics or related field.

    Have some knowledge of pathway analysis approaches and experience in applying machine learning techniques to noisy data sets.

    Highly motivated and a self-starter, with the ability to work efficiently with minimal supervision. Additional education may substitute for required experience and additional related experience may substitute for required education, to the extent permitted by the JHU equivalency formula.


    The position is located in Research Triangle Park, North Carolina at the National Center for Computational Toxicology of the US Environmental Protection Agency EPA and partly at the Johns Hopkins Center for Alternatives to Animal Testing, Baltimore MD.


    Please contact:
    Dr. rer. hum. biol. Andre Kleensang, Research Associate
    Johns Hopkins Center for Alternatives to Animal Testing (CAAT)
    Johns Hopkins University
    Bloomberg School of Public Health
    615 N. Wolfe St., W7032
    Baltimore, MD, 21205
    Phone: +1 410 614 4971

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