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    Opportunity: Post-doctoral Research Scientist (#IRC88553) -- Functional Genomics of Multiple Sclerosis @ University of Oxford -- Oxford, UK
    Submitted by Dr Vivienne Collins; posted on Wednesday, April 17, 2013


    We are looking for a motivated and enthusiastic post-doctoral scientist to join Dr Sreeram Ramagopalan's group at the MRC Functional Genomics Unit within the University of Oxford. You will join a research group that has established an international reputation for neurological disease genomics and vitamin D signaling. Multiple sclerosis (MS) is the commonest disease of the central nervous system to cause permanent disability in young adults. The disease develops in a genetically susceptible population as a result of environmental exposures. Current work in the group investigates the functional consequences of known risk factors that increase susceptibility to MS in order to fully understand the trajectory of disease processes underlying MS causation.


    The post will provide core biological and computational expertise in disease genomics and in next-generation sequence analysis.


    With a PhD / DPhil in the field of computational biology, bioinformatics, statistical genetics or comparative genomics, experience of scripting (e.g. Perl/Python) and advanced UNIX/linux skills are essential. Expertise in sequence analysis in biological research, current bioinformatics tools and resources, functional genomics, neuroscience and method development will also be desirable. Excellent organisational and communication skills will be required, together with the ability to work well within a team.


    You will work in the MRC Unit within the Department of Physiology, Anatomy and Genetics at the University of Oxford. The Functional Genomics Unit is a world-renowned centre for comparative genomics and research into neurological disorders and includes the groups of Professor Chris Ponting and Professor Kay Davies. We offer excellent computational and laboratory facilities in the modern Henry Wellcome Building of Gene Function. Additional information about the Unit can be found at, whilst informal enquiries can be made to Dr Sreeram Ramagopalan at sreeram.ramagopalan[at] For further information about the MRC please visit


    Depending on experience, you will be appointed to either a 3 year Career Development Fellowship or an open-ended Investigator Scientist position, with starting salary in the range GBP 26,282 to GBP 31,686 pa. This position is available immediately and provides opportunities to develop research project skills and develop collaborative links with colleagues within the University of Oxford and elsewhere.

    You will be entitled to benefits including 30 days annual leave, an excellent pension scheme and access to MRC training.


    Applications are handled by the RCUK Shared Services Centre; only online applications will be accepted. To apply please upload your CV, accompanied by a covering letter and any other relevant attachments (e.g. research publications) to Please make sure that you include the IRC88553 reference in the filename. Applicants who would like to receive this advert in an alternative format (e.g. large print, Braille, audio or hard copy), or who are unable to apply online should contact us by telephone on 01793 867003. Please quote the appropriate reference number when calling (IRC88553).


    Application deadline: 24 April 2013. Interviews to be held: 15 May 2013.

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