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BACKGROUND

We are seeking an experienced bioinformatician/programmer with a strong biological interest, or a biologist with extensive experience in bioinformatics.

Our team develops software (e.g. PhenoDigm and Exomiser) to help the scientific community understand the role of genes in human disease through the use of mouse as a model organism. Use of mouse phenotype data allows us to prioritise the variants identified by next-gen sequencing of patient samples as well as to understand the possible mechanism of action through model organism studies.

The Wellcome Trust Sanger Institute plays a central role in a number of large-scale international projects including the International Knockout Mouse Consortium (IKMC; http://www.knockoutmouse.org) and the International Mouse Phenotyping Consortium (IMPC; http://mousephenotype.org). The latter will generate the first complete catalogue of mammalian gene function. The next few years promise to bring a wealth of challenge and excitement for our group, in terms of the variety of work we will encounter, the scale of throughput that we will support and the implications that the work will have in the fundamental study of gene function in mammals.

This is an exciting opportunity to bring your data analysis skills to our team to support our leading-edge research into how gene mutations lead to human disease. You will work collaboratively with biologists and other informatics staff within our consortia to generate publications as well as contributing to the development of new software tools within our team.

REQUIREMENTS

PhD or MSc in a relevant area of bioinformatics, biology or computational biology
Experience of developing analysis pipelines in high level scripting languages
A good working knowledge of database schema design and advanced SQL query development.
An ability to learn quickly on the job.
We work as a close team, so good communication skills in the context of the team are important.

PREFERENCES

A good understanding of statistical analysis
Prior experience in ontologies and semantic querying
A good understanding of biology, particularly in the context of human disease
Experience of MySQL
A strong interest in this science and ability to learn fast is key. The campus runs frequent courses to allow staff to augment their technical skills.

LOCALE

A first names culture, informal dress code and an active company social calendar, all set in modern offices in the 55 acres grounds of Hinxton Hall and associated wet land reserve.

TERMS

This position is offered on a fixed term until 31st July 2016.

COMPENSATION

Salary range from GBP 29750 to GBP 37,525 per annum plus excellent benefits.

HOW TO APPLY

Please go to: https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=166037 to register and apply online.

DEADLINE

Applications will be considered on an on-going basis.

Discussion forums: Opportunity: Senior Bioinformatician -- Mouse Informatics Group (#81487) @ Wellcome Trust Sanger Institute -- Hinxton/Cambridge, UK

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