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    Opportunity: Lead Bioinformatics Scientist (Next Generation Sequencing) (#42531) @ SRA International -- Atlanta, GA (US)
    Submitted by John M. Greene, Ph.D.; posted on Thursday, July 11, 2013



    SRA is seeking a Lead Bioinformatics Scientist with end-to-end complete life cycle experience in analysis and workflow/pipeline development for major Next Generation Sequence (NGS) platforms, including Illumina, IonTorrent, and PacBio. The ideal candidate will be a highly skilled professional with broad experience in bioinformatics, including comparative genomics, Next Generation Sequence analysis, and high throughput genomic analysis pipeline development. Additionally, this position requires demonstrated competency in translating NGS results into meaningful biological insights using contemporary methods including variant analysis, comparative genomics, phylogenetic methods, and integration with other information types.

    In this role, you will lead a small team of skilled informaticians focused on leveraging NGS capabilities to develop the next generation of surveillance and laboratory diagnostic tools used in the global fight against disease. Position is for full time employment with SRA and will be based in our Atlanta, GA office, working normal business hours Monday through Friday.

    Key responsibilities will involve you being hands on to perform and to direct a small team in the following:
    • Building and supporting cutting-edge pipelines for the analysis and interpretation of NGS data from sequence production to variant calling and interpretation.
    • Participation in the technical development process of an emerging NGS surveillance platform.
    • Implementation of state-of-the-art computational methods, and developing innovative approaches to software challenges that touch all aspects of NGS data analysis.
    • Conduct programming and/or scripting using languages such as Perl, Python, Java and/or C++
    • Provide expertise in algorithm generation and statistical and computational methods for the analysis of complex, high-throughput biological data.
    • Analysis of large-scale genomic datasets acquired internally and through collaboration with others using statistical/ mathematical packages such as R and/or MATLAB.
    • Ensure software adheres to appropriate government and regulatory compliance requirements.
    • Maintain expertise in the science and application of genomic technologies.
    • Provide professional grade reports on ongoing sequencing, analysis, and surveillance activities.
    • Work with software development team members to mature and integrate analytical tools/pipelines into user accessible tools/interfaces in UNIX/Linux and high performance computing environments.
    • Serve as a subject matter expert to guide complex software development activities.


    • Ph.D. in biology, computational biology or related and 10+ years' experience or equivalent combination of education and experience
    • 2+ years experience in bioinformatics & Next Generation Sequencing (NGS) data analysis
    • Demonstrated fluency in UNIX/Linux computing environments
    • Demonstrated programming and/or scripting experience in languages such as Perl, Python, Java and/or C++
    • Experience in pipeline generation and/or computational methods implementation


    • Ph.D. in Bioinformatics, Biostatistics or Computational Biology or other relevant discipline preferred.
    • Experience with High Performance Computing environments
    • Strong in statistical/ mathematical packages such as R/MATLAB
    • Comfortable working in a dynamic, fast paced environment
    • Experience with multiple Next Generation Sequencing (NGS) technologies


    Full Time Employment with SRA International


    Atlanta, GA




    Please apply directly online via to job #42531: Lead Bioinformatics Scientist.


    We would like for someone to start as soon as possible and will stop searching when we find the right person. A likely start date will be around August, but there is some flexibility here.

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