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    Opportunity: Bioinformatician I (#400751084) @ Duke Center for Human Genome Variation -- Durham, NC (US)
    Submitted by Amy Roberson; posted on Wednesday, August 14, 2013


    The Center for Human Genome Variation in the Duke School of Medicine is a pioneer in human genetics and in clinical DNA sequencing analysis with a primary focus on identifying and biologically characterizing genetic variation underlying human disease. The CHGV Bioinformatics Team is seeking a talented, highly motivated computer science or bioinformatics graduate to participate in the operation and ongoing development of automated pipelines for high-throughput sequencing data analysis. This position presents a unique opportunity to acquire hands-on genomics experience while operating at the forefront of clinical medicine.


    The successful candidate will develop, implement, and test novel pipeline software, provide support for the production sequence analysis QC and analysis systems, and research/evaluate/integrate the performance of novel and third-party bioinformatics tools.


    Qualified candidates should have a B.S. in the Biological Sciences with demonstrable computational skills or a B.S. in Computer Science with experience in computational biology, bioinformatics, clinical informatics, or related field. Software development experience with strong computational/programming skills in UNIX command-line environment & associated tools (awk, sed, vim, etc.), programming languages including Perl, Python, and Java, basic relational database query (with standard SQL) and schema design, and cluster computing (e.g. SGE, LSF, or PBS).


    Preferred qualifications include, demonstrable experience with bioinformatics methods and software pertaining to high-throughput sequence analysis including read alignment, variant calling, & annotation, and case/control association analyses; 3 years of experience in developing automated pipeline software; strong understanding of software engineering concepts including OOP design, unit testing, version control, documentation, and release engineering; and familiarity with Apache Hadoop Ecosystem technologies (e.g. MapReduce, Pig, & Impala)


    Interested candidates should apply to Requisition #400751084 on the Duke employment website ( and submit a resume to:

    Attn: Jonathan Keebler
    Center for Human Genome Variation
    Durham, NC 27708
    Email: jonathan.keebler[at]

    Please note "Bioinformatician" in the subject line.


    Duke University is an Equal Opportunity/Affirmative Action Employer.

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