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BACKGROUND

Project Title: Annotation, assembly and metabolic reconstruction of the Alpine Marmot genome

Situated in Mill Hill, North West London, the MRC National Institute for Medical Research is the largest MRC institute, supporting some 70 research groups and 500 bench scientists. The Institute provides excellent training for researchers in a multi-disciplinary environment and is equipped with state of the art facilities, including genetic modification of mice, imaging, histology, and high throughput sequencing.

We are recruiting for a Postdoctoral Scientist (Career Development Fellow) to work on the genome of the alpine marmot (Marmota marmota). Alpine marmots are descendants of pleiocene rodents, who failed to re-adapt to warm climates. This restricted their existence to a few ecological niches, such as high-altitude mountain regions in the central Alps. Marmots are social and largely monogamic animals that have been genetically isolated for > 20,000 years, manage to survive with 1.2 kg body fat for 8 months, and have interesting features to adapt their body temperature. This makes them unique genetic models to study both metabolism and climate adaptation. This postdoc is to annotate the marmota genome, and to use this sequence to perform a genome-scale reconstruction of the mamota metabolic network in silico.

For more information please visit Lab webpage: http://www.nimr.mrc.ac.uk/research/markus-ralser/, http://ralser.sysbiol.cam.ac.uk

REQUIREMENTS

You should have a PhD (or be in the final stages of completion) in Biology, Mathematics, Computational Biology or Physics, with a strong interest in genome biology, experience with next generation sequencing data and genomics is desirable.

COMPENSATION

Salary range is from GBP 33,155 per annum inclusive of London Allowance. MRC final salary Pension Scheme is available.

HOW TO APPLY

Applications are handled by UK Shared Business Services. To apply please visit our job board at http://www.topcareer.jobs. Enthusiastic candidates are encouraged to apply with a cover letter, a full curriculum vitae and the contact information of at least two referees (please save the reference IRC116893 in the filename).

Candidates who would like to receive this advert in an alternative format (e.g. large print, Braille, audio or hard copy), or who are unable to apply online should contact us by telephone on 01793 867000. Please quote the reference number in all correspondence.

Informal enquiries can be made to: Dr. M Ralser email: mr559[at]cam.ac.uk

DEADLINE

Closing date: 29 November 2013

Discussion forums: Opportunity: Postdoctoral Scientist (#IRC116893) @ MRC -- London, UK

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