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    Opportunity: Genome Annotation Specialist @ Computercraft -- Bethesda, MD (US)
    Submitted by Computercraft Corporation; posted on Thursday, April 17, 2014


    Computercraft seeks a Genome Annotation Specialist to work with the National Center for Biotechnology Information's (NCBI) eukaryotic genome annotation pipeline. The successful candidate will generate annotation on genome assemblies from a wide variety of organisms using data deposited in the public sequence databases. The genome annotations produced contribute data to the NCBI Reference Sequence (RefSeq) project, Gene database, BLAST and Map Viewer genome browser and are used by the scientific community around the world.

    This is an exciting opportunity to apply your biological knowledge and computer expertise while using state-of-the art computational tools and databases. The successful candidate will work onsite at the National Institutes of Health, National Center for Biotechnology Information (NCBI) in Bethesda MD.


    • Select appropriate data sets to be used as evidence for making gene models for a particular organism
    • Set up production runs of the genome annotation pipeline
    • Monitor genome annotation runs, investigate failures and re-run failed steps
    • Distribute the annotation products to various NCBI resources
    • Set up and execute runs to train gene prediction software on new organisms
    • Evaluate and test new releases of the genome annotation pipeline software
    • Collaborate with other biologists and programmers to improve the genome annotation process and the quality of annotation produced
    • Help expand and improve the annotation reports provided for each annotation release
    • Contribute to public documentation for the genome annotation pipeline
    • Investigate errors, inconsistencies and deficiencies in the data stored in NCBI's Assembly resource and then use web-based interfaces, command-line tools and specialized databases to correct the genome assembly data


    • Biology knowledge (minimum: Masters of Science in a Biological field, or equivalent)
    • Experience with genomics desirable
    • Linux/UNIX experience
    • Strong organizational, logic and problem-solving skills
    • Strong verbal and written communication skills
    • Ability to work as part of a team and to collaborate with other scientists
    • Flexibility to respond quickly to new priorities
    • Detail-oriented perspective
    • Scripting experience in shell, Perl
or Awk desirable
    • Interest in contributing to public database resources


    To apply for this position or learn about other Computercraft job opportunities, please visit the Careers section of our website: OR[...]d=105


    Computercraft offers a competitive salary and an excellent benefits package including health insurance with 100% company paid premiums, 401K program with matching, paid time off and holiday pay, life insurance, flexible spending and disability coverage. We offer an excellent work life balance with a standard 40 hour work week and the chance to work with accomplished scientists at NIH/NCBI.


    Computercraft is an equal opportunity employer.

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