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BACKGROUND

We are seeking an experienced Senior Software Developer to join our development team providing informatics support for the High-Throughput Gene Editing team. We develop bioinformatics tools to assist in, for example, the design of genomic knockout constructs, CRISPR-Cas9 experiments and automated alignment analysis for quality control of targeted clones. Additionally, we develop web services to implement a LIMS (Laboratory Information Management System) for tracking scientific data generated in our stem cell engineering lab, as well as more bespoke support for our research groups in mouse and human stem cell engineering. See http://www.sanger.ac.uk/science/groups/stem-cell-informatics for more information on the work we do.

RESPONSIBILITIES

You will become part of a relaxed but professional software development team, with access to world class computing resources and many opportunities for furthering your knowledge of programming for bioinformatics and genomics, whether within the web framework or on our extensive compute farm.

This role involves gathering user requirements (in an informal way) and discussing the impact on current systems with the Senior Scientific Manager in the group and other members of the informatics team. We operate separate ticketing systems to manage user requirements and functional implementation. We develop primarily in modern Perl using a web stack based on PostgreSQL, Catalyst (for MVC support) and DBIx::Class. Legacy systems we still support use Oracle as the database layer. However, proficiency in programming any current language is more important than specific Perl experience.

Our user interfaces rely more and more on JavaScript and we use the ExtJS framework for some of our views.

There is substantial Perl expertise in the group and this opportunity could be a good way for appropriate candidates to get up-to-date with current Perl coding methodology.

Our LIMS is used to support many other groups, both within the Sanger Institute and around the world. WGE is recognised as world class software for designing important genome editing experiments in many leading research groups.

You will contribute code to our source code repositories on GitHub (https://github.com/htgt) as part of our collaborative and agile-enlightened approach to coding.

We welcome applications equally from those who wish to work full time (37 hours) or for a minimum of 30 hours per week via a flexible working arrangement.

REQUIREMENTS

Bachelor's degree or above in computer related sciences, or equivalent experience
Evidence of a high level of competence in a modern scripting language based on C-style syntax using a relational database
Ability to design and run complex database queries in SQL
Experience of developing and delivering a quality product within fixed deadlines
Ability to prioritise tasks to ensure the right things are done at the right time
Highly developed problem solving skills

PREFERENCES

Programming in Modern Perl
Some experience with JavaScript programming and web development
Evidence of having successfully worked in a collaborative, project-focused software team
Evidence of having successfully created interfaces that link with and enable extraction/reporting/display of data from large, complex databases into a web environment
Experience and understanding of bioinformatics and familiarity with genome data

LOCALE

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited's 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society. To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

COMPENSATION

£31,498 - £39,729 pa depending on experience

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

HOW TO APPLY

To apply click on the link: https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=308547

Please include a covering letter and CV with your application.

DEADLINE

Closing date: 23rd April 2017

POLICY

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

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