Bioinformatics.org
[NEU MS in Bioinformatics]
Not logged in

Bioinformatics.org
Membership (37278+) Group hosting [?]

Careers
About bioinformatics
Bioinformatics training
Bioinformatics jobs

Research
All information groups
Online databases Online analysis tools Online education tools More tools

Development
All software groups
FTP repository
SVN & CVS repositories [?]
Mailing lists

Forums
News & Commentary
Jobs Forum
(Career Center)

News & Commentary - Message forums

Gene name errors introduced by Excel
Submitted by Marcos Oliveira de Carvalho; posted on Thursday, July 29, 2004
Submitter A research article at BMC Bioinformatics:

BACKGROUND:
When processing microarray data sets, we recently noticed that some gene names were being changed inadvertently to non-gene names.

RESULTS:
A little detective work traced the problem to default date format conversions and floating-point format conversions in the very useful Excel program package. The date conversions affect at least 30 gene names; the floating-point conversions affect at least 2,000 if Riken identifiers are included. These conversions are irreversible; the original gene names cannot be recovered.

CONCLUSIONS:
Users of Excel for analyses involving gene names should be aware of this problem, which can cause genes, including medically important ones, to be lost from view and which has contaminated even carefully curated public databases. We provide work-arounds and scripts for circumventing the problem.

The full article is open-access and gratis to download:
[link]

Expanded view | Monitor forum | Save place

Start a new thread:
You have to be logged in to post a reply.

 

Copyright © 2016 · Scilico, LLC