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Software: inGAP: New software for analyzing next-gen genomic data
Submitted by fq; posted on Monday, June 08, 2009 (1 comment)
inGAP (Integrated Next-gen Genome Analysis Platform) is an integrated platform for next-generation sequencing projects, the core function of which is to detect SNPs and indels using a Bayesian algorithm.
FEATURES
- No read length restriction
- Can detect most small indels in either single-end or paired-end data sets
- Has a strong capability to identify variants based on a relatively divergent reference genome
- Provides a user-friendly graphic interface
- Can be used to detect intraspecific polymorphisms (including SNPs and indels) based on a pairwise comparison of multiple whole genomes
- Employs a global heuristic searching approach to layout contigs based on one or more reference genomes
- Also provides a handful of bioinformatic tools for read simulation, mutation incorporation, format conversion, etc.
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