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Opportunity: Post-Doctoral Research Fellow (#SC-23207) @ Fred Hutchinson Cancer Research Center--Seattle, WA (US)
Submitted by Alysha Duran; posted on Friday, July 16, 2010
BACKGROUND:
Fred Hutchinson Cancer Research Center, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, the Center’s five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Hutchinson Center, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Join us and make a difference!

RESPONSIBILITIES:
The Bielas lab (http://labs.fhcrc.org/bielas/), in the Molecular Diagnostics Program at the Fred Hutchinson Cancer Research Center, studies the fundamental and clinical implications of nuclear and mitochondrial DNA mutations in the pathogenesis of cancer and age-related disease. Recent data attained with the use of an exceptionally sensitive array for quantifying both nuclear and mitochondrial mutations, have focused our principal research interest in the application of DNA mutations as novel molecular disease markers for diagnostics. We are currently investigating the prevalence of cancer-associated mitochondrial and nuclear mutations disseminated in bodily fluids as a marker for early detection, minimal residual disease, and recurrence. We have also initiated studies to explore the utility of genome mutational load, as an additional more quantitative index, of tumor therapeutic response, clinical stage, and progression.

We are recruiting a highly motivated scientist at the PhD level to carry out fundamental DNA repair and mutation research, which investigates the mechanisms of disease pathogenesis – and promotes the translation, development and implementation of DNA-based biomarkers. We would especially like to encourage graduate students at the end of their training program, who are eligible for participation in NIH-funded training grants and fellowships to apply.

REQUIREMENTS:
- PhD in a relevant biological field, with a strong background in molecular and cellular biology including: cloning, transfection/infection of cells, PCR, and Southern/Northern/Western blotting

- Experience in tissue culture, QPCR, mutational assays, and FACs is highly desirable.

- Candidates should be able to demonstrate a track record of independent productive research, show willingness to help guide junior lab members, have strong organizational, written, and verbal skills, and possess the ability to work both independently and as part of a laboratory team.

TERMS: Full-time position

LOCALE: Seattle, Washington

COMPENSATION:
Salary based on NIH guidelines + excellent benefits

HOW TO APPLY:
Please send a letter summarizing previous work experience and research interests, a complete CV, list of publications, and contact information for three professional references to:

Scott Canavera
Scientific Recruiter
Human Resources, J1-105
Fred Hutchinson Cancer Research Center
P.O. Box 19024
Seattle, WA 98109-1024
scanaver[at]fhcrc.org
FAX 206.667.4051

Electronic submissions are preferred.

ARTICLE: Please refer to position number SC-23207 in your application.

The Fred Hutchinson Cancer Research Center and the Seattle Cancer Care Alliance are equal opportunity employers, committed to workforce diversity.

DEADLINE: Open until filled



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