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    Opportunity: Postdoctoral Associate (#487) @ The Broad Institute--Cambridge, MA (US)
    Submitted by Laura Bonfitto; posted on Thursday, February 17, 2011


    A postdoctoral associate position is available for a highly-motivated scientist to join a dynamic group in computational chemical biology research at the Broad Institute. The position is an exciting opportunity to perform cutting-edge research within the Broad's Chemical Biology Program, interacting with chemists and biologists in the course of method development in cheminformatics and high-throughput data analysis. The position will report to the Director, Computational Chemical Biology Research and aim to apply state-of-the-art computational approaches to understand structure-activity relationships in the context of the consequences of synthetic chemistry decisions on measured biological profiles of small molecules. These studies are consistent with the aims of an cheminformatics project within the context of a larger chemistry program project grant, with applications toward lead hopping, target identification, off-target effects, and understanding mechanisms of compound action in the context of biological networks.


    • Ph.D. degree in cheminformatics, computational biology, bioinformatics, or a related field
    • experience with small-molecule structure data, chemical fingerprints, similarity and diversity
    • familiarity with chemical information and cheminformatics databases (e.g., ChEMBL, PubChem)
    • solid foundation in basic statistics and quantitative data-analysis, data-mining, and pattern-recognition methods.
    • understanding of modern biological screening and profiling methods, including gene-expression and other high-content methods
    • experience with biological pathway data and network analysis
    • ability to work both independently and in the context of collaborative team
    • excellent organization skills and oral/written communication skills
    • strong analytical and problem-solving skills


    The Broad Institute was launched to pioneer a new model of collaborative biomedical science that would transform medicine. To accomplish these goals, we have built an amazing team of talented Broadies who work together to realize this transformation.

    We are always looking for new Broadies to join our team and help us tackle important problems at the cutting edge of science.

    The Broad community includes professional scientists from many disciplines, administrative staff, and students. We seek to cultivate an interdisciplinary, goal-oriented work environment that unleashes scientific creativity and empowers our people to pursue ambitious and critical projects.

    Our work transcends traditional academic boundaries, giving Broad employees and affiliates access to an unparalleled biomedical research community across the Harvard and MIT communities and beyond.

    The Broad Institute is committed to providing its employees with a competitive compensation and benefits package. We recognize the need for our employees to have a balance between work and personal life. To that end, our benefit plans and options reflect our desire to promote an environment that supports the health, diversity, and general wellbeing of our employees.

    All Broadies also have access to world-class research and state of the art technology and are fully supported in their professional development, pushing the envelope for further growth.


    Please apply via our website:[...]enter. Position 487.


    The Broad Institute is an equal opportunity employer.

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