[NEU MS in Health Informatics]
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    Opportunity: Analysis Pipeline Manager (#81081) @ Wellcome Trust Sanger Institute--Hinxton/Cambridge, UK
    Submitted by Sam Bowker; posted on Thursday, January 12, 2012


    The Wellcome Trust Sanger Institute is a world leader in the use of large-scale sequencing, informatics and analysis of genetic variation. We use sequence data to further our understanding of infectious disease and generate resources of lasting value to biomedical research.

    The Kwiatkowski Group of the Sanger Malaria Programme is leveraging recent revolutionary advances in genome technology to understand the role of natural genetic variation in protective immunity against malaria in humans, and pathogenicity and drug resistance in malaria-causing parasites. This work involves large-scale epidemiology and cutting-edge sequencing technology, combined with novel programming and informatics to manage and analyse the data.


    We have a unique opportunity for an experienced programmer to develop, implement and manage systems for the processing and analysis of large-scale genome sequencing and genotyping data from Plasmodium, Anopheles and human populations.

    Our work is highly collaborative and the post-holder will work closely with other informatics specialists in our team and with partners within and beyond the Institute to establish accurate and efficient analysis pipelines for high-throughput sequencing data using both established and new sequencing technologies. As such, strong communication skills and willingness to work collaboratively in a team setting are essential.


    • PhD in computer science or equivalent experience
    • Proven track record in the production and delivery of complex and interlinked solutions to end users (one or more large projects)
    • Proven track record of producing, testing and delivering defined solutions at an enterprise level
    • Experience of developing applications on Linux or Unix operating systems
    • Strong teamwork and communication skills
    • Strong programming skills
    • Strong database development skills
    • Strong problem solving skills


    • Significant level of experience with management of genetic or genomic data and understanding of principles of statistical genetics
    • Experience of web application development
    • Fluency in Java, JavaScript, C++ and Perl
    • Experience of MySQL, SQLServer and Oracle


    The Institute has excellent purpose built facilities on the Genome Campus, Hinxton on the outskirts of Cambridge. We offer a comprehensive range of benefits including a final salary pension scheme and excellent on-site facilities. Further details can be found on our website


    To submit your CV and apply for this job please go to to register and apply on line.


    The closing date for applications is 27 January 2012

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