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    Opportunity: Senior BIOINFORMATICIAN - Pathogen Informatics (#81084) @ Wellcome Trust Sanger Institute--Hinxton/Cambridge, UK
    Submitted by Sam Bowker; posted on Wednesday, January 18, 2012


    The Wellcome Trust Sanger Institute is a world leader in genomic research, with an expanding scientific programme dedicated to understanding gene function in health & disease.

    The Wellcome Trust Sanger Institute, based south of Cambridge, is one of the world's leading genomic research centres funded primarily by the Wellcome Trust. Our mission is to use genome sequences to advance understanding of the biology of humans and pathogens in order to improve human health.

    Parasitic worms are responsible for more than one billion human infections globally and have a devastating impact on livestock and agriculture. The parasite genomics group at the Wellcome Trust Sanger Institute (WTSI), is undertaking a major project to sequence the genomes of those nematode species that have the greatest impact on human disease (especially in the developing world) and their most common laboratory models.

    WormBase ( was established in 2000 and has grown from a database focusing on a single model nematode species (C. elegans), to a rapidly expanding resource containing the genomes of nematode species produced by the WTSI and elsewhere. Ensembl (est. 2000) is a project based at the European Bioinformatics Institute (EBI) and the WTSI that produces genome databases. Recently, the Ensembl Genomes project was launched at the EBI to extend the Ensembl database across taxonomic space.


    We are seeking a Senior Bioinformatician to join the parasitic genomics group and work alongside the WormBase and Ensembl Genomes teams to produce a high quality set of gene predictions and first-pass annotation for more than 30 nematode genomes currently being sequenced at the WTSI. In addition to producing data of enormous benefit to the parasitic-worm research, we envisage that if successful, the project will lay the foundations for work to be undertaken by WormBase during its next funding cycle.


    • You will need to have a strong background in bioinformatics indicated by a relevant PhD (or MSc plus extensive practical experience).
    • Perl or Python programming at an advanced level
    • Knowledge and experience of UNIX / LINUX on an advanced level
    • Experience of dealing with large data sets and running software on a compute farm
    • Highly developed problem solving skills
    • Excellent communication skills
    • Good theoretical knowledge of DNA & RNA bioinformatics


    This is a fixed term post, funded as part of the NIH/MRC-funded Wormbase project until 31st March 2013.


    The Institute has excellent purpose built facilities on the Genome Campus, Hinxton on the outskirts of Cambridge. We offer a comprehensive range of benefits including a final salary pension scheme and excellent on-site facilities. Further details can be found on our website


    To submit your CV and apply for this job please go to to register and apply on line.


    Closing Date: 19th February 2012

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