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    Opportunity: Senior BIOINFORMATICIAN MalariaGEN (#81125) @ Wellcome Trust Sanger Institute--Hixton/Cambridge, UK
    Submitted by Sam Bowker; posted on Wednesday, March 14, 2012


    MalariaGEN is a data-sharing community working to develop new tools to control malaria by integrating epidemiology with genome science ( The resource centre that supports MalariaGEN is based at both the Sanger Institute near Cambridge and at the Wellcome Trust Centre for Human Genetics at the University of Oxford. MalariaGEN is therefore able to draw on both the Sanger Institute's world leadership in genomics and on Oxford University's world leadership in global health and genetic epidemiology.

    MalariaGEN aims to produce global data on natural genetic variation in parasite, mosquito and human populations, and to deliver these data via the website, alongside web tools which add value by enabling people to explore, understand and analyse the data. Some of these web and data products are intended for unrestricted use by the malaria research and public health community, to inform future research directions and malaria control policy. Other web and data products are being developed for private use by researchers contributing to MalariaGEN community projects, and provide a key incentive to participation in MalariaGEN, e.g., secure web tools providing access to fine-grained genetic data on individual samples.


    We have an opportunity for an experienced Bioinformatician to take a key role in design, implementation and evaluation of new analytical methods and the design, implementation and operation of analysis pipelines. This relates to genome sequencing, genotyping and population genetic data from Plasmodium, Anopheles and human populations.

    Our work is highly collaborative and the post-holder will work closely with other informatics and analysis specialists in our team and with partners within and beyond the Institute. Strong communication skills and willingness to work collaboratively in a team setting are essential.


    • A good first degree in a scientific, computing or other numerate subject
    • A post graduate qualification in bioinformatics or related subject
    • Post-doctoral or equivalent professional experience working in a bioinformatics role
    • Exemplary programming skills, in one of more of Perl, R, C++ and Python
    • Experience of applied statistics and statistical computing
    • Experience developing and operating data analysis pipelines, working with large data volumes and high-performance computing
    • Strong scientific discipline
    • Proven ability to work as part of a team and to develop strong collaborative working relationships
    • Excellent written and oral communication


    • Experience with managing and processing next-generation sequencing data
    • Experience of detecting and analysing genetic variation
    • Knowledge and interest in the life sciences, genomics and public health


    Due to the highly collaborative nature of the role the position can either be based at the Sanger Institute or at the University of Oxford


    This position is offered for a fixed term of 3 years.


    Salary range for this position is GBP 27589 to GBP 38067 per annum dependent on experience


    To submit your CV and apply for this job please go to to register and apply on line.

    For more information about the role please contact the Senior Group Leader, Dominic Kwiatkowski, on Dominic.Kwiatkowski[at] or Dominic[at]


    Closing date for applications – 13th April 2012

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