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    Opportunity: Software Engineer @ Nodality -- South San Francisco, CA (US)
    Submitted by David Spellmeyer; posted on Wednesday, August 08, 2012

    BACKGROUND

    Nodality is looking for an individual who is motivated to apply his/her programming skills to the high-impact area of personalized medicine. You will be part of a team that is working to make a difference in the lives of patients by advancing research and clinical biology to individualize medicine.

    Our proprietary Single Cell Network Profiling (SCNP) technology quantifies intracellular protein function of individual cells in a high content and high throughput format. We have developed robust and reproducible assays that quantify intracellular network responses for systems biology research. We apply this technology to drug characterization and therapeutic profiling, with the aim of developing highly predictive algorithms for patient stratification and therapeutic treatment selection. This approach interrogates cell signaling networks and pathways downstream of SNPs, gene and protein expression, providing an integrated, functionally relevant view of disease biology.

    Nodality offers a rich environment in which you will make significant contributions to designing and building Nodality's intranet and suite of tools used in laboratory and analysis workflows to extend our Lab Informatics platform. You will have the opportunity to work with, and learn from world-class experts in a wide range of disciplines including, biology, computational sciences and translational medicine.

    Nodality's Lab Informatics platform is an internal tool used by biologists, clinical scientists, and laboratory specialists to manage reagents, patient samples, experimental setup, and backend data analysis. The platform is a combination of .Net, Python and Web technologies integrating several components including a rich user interface, database, and backend computational engine to support a variety of workflows. Agile practices are used to develop software in close collaboration with end users using both in-house and off-shore resources and with rapid release cycles. This platform has enabled increased efficiencies in all phases of generating data from experimental planning to execution and analysis. Your efforts will be key in improving the efficiencies through several additional rounds of development, deployment, and feature optimization.

    RESPONSIBILITIES

    • Work closely with research scientists, lab staff, and computational scientists to identify and implement key automation steps and process improvements.
    • Design, develop, integrate, and deploy related web application components including front end development, server-side development, and system integration.
    • Provide web application support for testing, debugging and applying incremental improvements in working laboratory environments, both in research and regulated environments.
    • Provide training, and troubleshooting for applications deployed to a diverse user base.
    • Comply with and help evolve process methodologies including source control, unit testing and coding standards.
    • Make recommendations for process improvements and new technologies that will make a positive impact on the laboratory and analysis workflow.
    • Collaborate with remote development teams.

    REQUIREMENTS

    • A bachelor's or master's degree in computer science and/or related field
    • 2+ years of industrial experience
    • Excellent verbal and written communication skills
    • Demonstrated ability working with end user biologists, clinical scientists, and laboratory technologists.
    • Demonstrated willingness to be hands-on, pro-active and flexible
    • Demonstrated ability to work in multi-disciplinary environment
    • Ability to craft a great user experience
    • Knowledge of JQuery, JavaScript, Python, HTML, XSLT, MySql
    • Knowledge of one or more of these items is highly desirable: Developer Express WinForms, SharePoint integration, software development in a regulated environment, with other programming languages
    • Understanding of relational database systems
    • Programming experience in Windows and Linux environments
    • Proficiency in Microsoft® Office tools
    • Knowledge of multicolor flow cytometry a definite plus
    • Knowledge of programming languages C# and/or C++ is a plus

    ABOUT US

    For more details about Nodality, please visit our website at www.nodality.com.

    LOCALE

    This position is based in Nodality's South San Francisco, California site.

    HOW TO APPLY

    Please submit your resume with cover letter to jobs[at]nodality.com. Principals only.

    POLICY

    Nodality is an equal opportunity employer. Nodality offers a competitive salary and benefits package including paid time off, health, dental, vision, long term disability and life insurance, as well as equity participation.

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