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    Opportunity: Senior Scientist -- CLINICAL INFORMATICS / Oncology Biomarker @ Genentech -- South San Francisco, CA (US)
    Submitted by Pamela; posted on Tuesday, October 30, 2012

    BACKGROUND

    Passionate About Science

    We're passionate and rigorous about our science. For more than 30 years, Genentech has been at the forefront of the biotechnology industry, using innovative science to develop breakthrough medicines that improve the lives of people with serious or life-threatening diseases.

    The following opportunity exists in our South San Francisco, California headquarters.

    RESPONSIBILITIES

    Genentech is seeking a highly motivated informatics Senior Scientist/Scientist to lead and support biomarker data analysis within the Oncology Biomarker Development (OBD) group in gRED. The incumbent is expected to leverage extensive computing infrastructure and existing pipelines to build and maintain quality controlled, data analysis, storage and reporting pipelines focused on state of the art molecular biomarker analysis platforms. A second focus will be translating complex biomarker data into useful diagnostic tools that can guide the understanding of drug activity in patient tumors or the identification of subsets of patients who may benefit from therapeutic intervention.

    The successful candidate is expected to closely collaborate and partner with biomarker, clinical and statistics scientists in early development, participate and contribute to team meetings, publish in high quality scientific, technical or medical journals, present at meetings and drive novel innovative informatics and data analysis strategies. The incumbent is expected to coordinate and enable data sharing/exchange and engage in collegial collaborations with scientists in the Bioinformatics Research department.

    The Senior Scientist/Scientist clinical informatics, OBD, will report to the Director of OBD-Dx within the Development Sciences Division of Genentech Research and Early Development. The individual will lead data analysis strategies for programs in both OBD predictive diagnostics (Dx) and pharmacodynamic (PD) groups. A key responsibility of this role will be to coordinate and engage with scientists and colleagues in the Bioinformatics Research department to enable the appropriate utilization of databases and analysis tools.

    REQUIREMENTS

    A PhD degree in a relevant scientific field (molecular biology, bioinformatics, statistics, computer science etc.) and a minimum of 7-10 years post-doctoral research in bioinformatics, computer science and/or statistics with experience in either academic and/or industry setting Expertise in a high-level programming and data analysis/visualization language such as R, MATLAB or Perl are required. Though not required, familiarity with R and Bioconductor is a plus, as is low-level programming and relational database experience is a plus. Demonstrated record of achievement in field of expertise as evidenced by first or co-author publications in top-tier journals is required. The candidate must have experience in analysis of high throughput genomic data (microarray, next gen sequencing, mass spec etc.) Experience working with clinical data is preferred. Extensive statistical expertise is also preferred.

    COMPENSATION

    Passionate About Our People

    We recognize that our people are our most important asset. It's why we foster an inclusive environment that encourages diversity and offer competitive healthcare and benefits to help you bring the best to the business and to your personal life.

    HOW TO APPLY

    Join us as we continue to tackle medicine's most challenging problems and live a life inspired. To apply for this job, visit roche.taleo.net/care[...]11480.

    Now a member of the Roche Group, Genentech has multiple medicines on the market for cancer and other serious illnesses.

    POLICY

    We are an equal opportunity employer.

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