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RESPONSIBILITIES

We are currently seeking a highly talented individual with a strong computational/IT background who seeks to use their computational skills to analyse large-scale data with important disease and population genetic ramifications. One focus will be to analyse and manipulate large-scale (GWAS) genotype and related data from thousands of mothers and babies with PreEclampsia (PE) in order to identify DNA variants that predispose to PE in maternal and/or fetal DNA. This position will also involve enhancing software that evaluates and visualizes the genomic locations of admixed DNA in subjects with ancestry from two or more genetically distinct groups, in order to increase the software's capabilities and extend its use to whole genome sequence data. The position will provide opportunities for ingenuity when applying computational approaches to address a variety of genetic analysis tasks and hence will provide opportunities to learn scientific and theoretical aspects of disease and population genetics in conjunction with the computational tasks performed.

Now is an extremely exciting time for the study of human genetic variation. As a world leader in human genomics, genome informatics, and whole genome DNA sequencing, the Wellcome Trust Sanger Institute (WTSI) is now focusing large-scale genotyping, DNA sequencing, and mathematical analysis on important disease and population genetic questions.

REQUIREMENTS

Essential Skills:

Extensive experience in quantitative science as evidenced for example by a degree in a relevant subject (e.g. Computer Science; Bioinformatics; Quantitative Genetics)
Demonstrated high level of software programming skill and knowledge
Firm grounding in mathematical/statistical/computational methods
Previous experience working with large-scale (empirical and/or simulated) datasets;
Strong interest in disease and the life sciences
Ability to communicate effectively with collaborators both internally and externally
Ability to maintain cordial, effective working relationships
Attention to detail and ability to work to tight timelines

Ideal Skills:

Knowledge of Perl, C++, UNIX/LINUX, Oracle and/or MySQL
Demonstrable good project management and organisational skills
Demonstrated proficiency in manipulating and querying large relational databases
Experience in applying computational methods to the analysis of genetic data
Track record in preparing scientific presentations and contributing to scientific publications
Some knowledge of website construction

TERMS

This is a 3 year fixed contract position

LOCALE

The location of this role is the Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge CB10 1SA

COMPENSATION

Salary range is from GBP 27,500 per annum dependent on experience

HOW TO APPLY

Go to: https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=159100

DEADLINE

Closing date for applications is 19th December 2012.

Discussion forums: Opportunity: Statistical Genetics Programmer -- BIOINFORMATICIAN @ Wellcome Trust Sanger Institute -- Hinxton/Cambridge, UK

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