MHC, or major histocompatibility complex is a gene complex found in jawed vertebrates. The genes found on this region of the genome include several important genes which encode proteins which are responsible for presenting peptides on the cell surface for inspection by cells of the immune system. In human, such genes are called HLA (human leukocyte antigen). MaHCO contains terms necessary for describing and categorizing concepts related to MHC, in general, and for a number of model species, and also for humans. Important resources include the international ImMunoGeneTics information system (IMGT), and the Immuno Polymorphism Database (IPD).
- Figure of upper classes of MaHCO (very large)
- Figure of a subset of classes including HLA allele examples (also very large)
April 13th, 2009
- Note that MaHCO.owl uses an import statement to include the classes found in MaHCO_HLA.owl. Please download both files if you intend to work offline.
- Dublin core: http://protege.stanford.edu/plugins/owl/dc/protege-dc.owl