OMIM :  NA

GENECARD : KRT20

CGAP : 84905

Cell Type Distribution

• Anatomic distribution of cytokeratin 20 is generally restricted to epithelia and their neoplasms. Chu P, Wu E, Weiss LM.

• Characterization of cytokeratin 20 expression in pancreatic and colorectal cancer. Wildi S, Kleeff J, Maruyama H, Maurer CA, Friess H, Buchler MW, Lander AD, Korc M.

Clinical

• Expression of cytokeratin 20 in the blood of patients with disseminated carcinoma of the pancreas, colon, stomach, and lung. Chausovsky G, Luchansky M, Figer A, Shapira J, Gottfried M, Novis B, Bogelman G, Zemer R, Zimlichman S, Klein A.

• CK 20 is overexpressed in pancreatic cancer and that it can serve as an excellent marker for metastatic pancreatic cancer. Wildi S, Kleeff J, Maruyama H, Maurer CA, Friess H, Buchler MW, Lander AD, Korc M.

• Survival of patients with CK 20 mRNA-positive findings was significantly shorter than that of negatively tested patients. Soeth E, Vogel I, Roder C, Juhl H, Marxsen J, Kruger U, Henne-Bruns D, Kremer B, Kalthoff H.

• Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies. Moll R, Lowe A, Laufer J, Franke WW.

Gene Frequency (Tumors)

• Adenosquamous carcinoma of the pancreas: a clinicopathologic series of 25 cases. Kardon DE, Thompson LD, Przygodzki RM, Heffess CS.

• Cytokeratins 7, 17, and 20 reactivity in pancreatic and ampulla of vater adenocarcinomas. Goldstein NS, Bassi D.

• Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. Chu P, Wu E, Weiss LM.

• Expression of cytokeratin 20: 22 of the 28 pancreatic carcinoma patients showed positive CK-20 expression. Chausovsky G, Luchansky M, Figer A, Shapira J, Gottfried M, Novis B, Bogelman G, Zemer R, Zimlichman S, Klein A.

Regulation

• CK 20 is overexpressed in pancreatic cancer. Wildi S, Kleeff J, Maruyama H, Maurer CA, Friess H, Buchler MW, Lander AD, Korc M.