[BiO BB] RE: BiO_Bulletin_Board digest, Vol 1 #25 - 2 msgs

Mon Apr 23 04:34:20 EDT 2001

Dear Peter,
I advice you to look at the IBM bluegene project about the predicting
tertiary structure of proteins from primary sequence means protein folding.
Here is the brief description of project
and you can find more info about supercomputers and aplication areas at IBM
site.

On December 6, 1999, IBM announced a $100 million research initiative to
build the world's fastest supercomputer, "Blue Gene", to tackle fundamental
problems in computational biology. The Blue Gene system will be capable of
performing more than one petaop/s (1,000,000,000,000,000 operations per
second). It will achieve this performance through a combination of massive
parallelism (1 million processors), and new computer architecture
approaches: the system will be built through the replication of a large
number of identical chips, each containing multiple processors, memory and
communication logic. Simultaneous multithreading will be used at each
processor to hide memory latency and simplify microprocessor design. The
Blue Gene project will use this computer for large scale biomolecular
simulation to advance our understanding of biologically important processes,
in particular our understanding of the mechanisms behind protein folding.

http://www.research.ibm.com/bluegene/

Huseyin Uysal

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Subject: BiO_Bulletin_Board digest, Vol 1 #25 - 2 msgs

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Today's Topics:

1. [Fwd: Junior Essay] (J.W. Bizzaro)
2. Re: [Fwd: Junior Essay] (J.W. Bizzaro)

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Message: 1
Date: Sat, 21 Apr 2001 17:46:21 +0000
From: "J.W. Bizzaro" <jeff at bioinformatics.org>
To: bbb at bioinformatics.org
Subject: [BiO BB] [Fwd: Junior Essay]
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Subject: [BiO Admin] Junior Essay
From: Peter Noble <raulfortis at hotmail.com>
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Hello,
My name is Peter Noble and I am currently attending
Colville High School in Colville, WA.  And as all juniors
are required at this school, I am writing an essay based on
a subject which has effected American history on some
level, most likely something that can be argued on its
importance.  I chose supercomputing and its uses.  As
supercomputing has many uses I am able to touch on only a
few sections, the medical field, nuclear research, etc.
Unfortunately I have run into a small problem in regaurds
to the medical field, it seems that about all I can find
information on is DNA analysis, which leaves me with a
small problem because not very much on a widescale level
has been produced from that information yet.  (Or at least
not that I know of) What I was hoping was maybe a
redirection of where I could find more information, say an
ailment which a cure was found for through the use of
supercomputing, or even an example of how I should look.
Any help you can offer would be most appreciated.

Thank you,
Peter Noble
Student

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Message: 2
Date: Sun, 22 Apr 2001 03:04:10 +0000
From: "J.W. Bizzaro" <jeff at bioinformatics.org>
To: bbb at bioinformatics.org, Peter Noble <raulfortis at hotmail.com>
Subject: Re: [BiO BB] [Fwd: Junior Essay]
Reply-To: bio_bulletin_board at bioinformatics.org

I would suggest taking a look at the THINK screensaver as well, a "fight
cancer at home" project:

http://members.ud.com/vypc/cancer/think.htm

It too is "Internet distributed computing" and not quite traditional
supercomputing.

Jeff B.

Jeff Ames wrote:
>
> Have you looked at the Fight AIDS at Home project?  It uses distributed
> computing, similar to the rc5 / distributed.net projects.  People
> contribute CPU cycles to protein modelling, supposedly to help researchers
> develop new drugs to fight AIDS/HIV.  I don't know of any published
> results yet, though.

--
J.W. Bizzaro                                jeff at bioinformatics.org
Director, Bioinformatics.org        http://bioinformatics.org/~jeff
"As we enjoy great advantages from the inventions of others, we
should be glad of an opportunity to serve others by any invention
of ours; and this we should do freely and generously."
-- Benjamin Franklin
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