[BiO BB] information on database

[kiran challapalli]

Hi 
I have two specific problems related to biology. i am
looking for the following information in the net.
Could anyone help me out?
Is there any database on small molecule inhibitors
which also has information on it's target protein and 
organism. 
Is there any database on  different mutations in
different mcorbial genomes that lead to resistance to
the drugs/inhibitors? 

I hope i am clear in putting the questions. 
Thank you in advance.
Kiran Kumar


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