[BiO BB] computational mutagenesis

[Dana Reichmann]

Iddo hi,

thanks for the suggestion, i'll check it,

I am more interesting on evaluation of changes upon mutation (structure 
and thermodynamic changes) when the structure of a wild type complex is 
known. Something similar to FOLDEFF program (from L.Serrano group) or 
Rosetta from D. Baker.

Thanks,
Dana


On Mar 10, 2004, at 7:50 PM, Iddo Friedberg wrote:

> Dana,
>
> Have you looked at the CAPRI site (http://capri.ebi.ac.uk/)
> and papers in Proteins?
>
> (http://www3.interscience.wiley.com/cgi-bin/jissue/104531597)
>
> Iddo
>
> Dana Reichmann wrote:
>> Hi all,
>> I am looking for good programs and algorithms for computational 
>> mutagenesis that can define hot spots in *protein-protein 
>> *interactions. I am interesting in different approach such as 
>> thermodynamical, structural etc. I want to understand what kind of 
>> approach are better, what is maximal prediction % of each.
>> Thanks a lot,
>> Dana
>
> -- 
> Iddo Friedberg, Ph.D.
> The Burnham Institute
> 10901 N. Torrey Pines Rd.
> La Jolla, CA 92037
> USA
> Tel: +1 (858) 646 3100 x3516
> Fax: +1 (858) 713 9930
> http://ffas.ljcrf.edu/~iddo
>