[BiO BB] computational mutagenesis
dana.reichmann at weizmann.ac.il
Wed Mar 10 13:30:30 EST 2004
thanks for the suggestion, i'll check it,
I am more interesting on evaluation of changes upon mutation (structure
and thermodynamic changes) when the structure of a wild type complex is
known. Something similar to FOLDEFF program (from L.Serrano group) or
Rosetta from D. Baker.
On Mar 10, 2004, at 7:50 PM, Iddo Friedberg wrote:
> Have you looked at the CAPRI site (http://capri.ebi.ac.uk/)
> and papers in Proteins?
> Dana Reichmann wrote:
>> Hi all,
>> I am looking for good programs and algorithms for computational
>> mutagenesis that can define hot spots in *protein-protein
>> *interactions. I am interesting in different approach such as
>> thermodynamical, structural etc. I want to understand what kind of
>> approach are better, what is maximal prediction % of each.
>> Thanks a lot,
> Iddo Friedberg, Ph.D.
> The Burnham Institute
> 10901 N. Torrey Pines Rd.
> La Jolla, CA 92037
> Tel: +1 (858) 646 3100 x3516
> Fax: +1 (858) 713 9930
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